are u saying u have no spark on cyl 1 and 4 or no spark to any of the plugs. if its all of them then i would say ur crank angle sensor is playing up, or worse
ecu.
if you have cyl 1 and cly 4 with no spark and u are sure that cly 1 and 4 coil and plug are fine, i would check the wiring to the
ecu, if ok then possibly the
ecu is not sending out the signal and would need replacing. Other thing to check is have you un-done a earth wire or has it high resistance ect. most coil packs will have a earth to the body some where hope this helps